Using an approach combining biochemistry, molecular biology, and genetics, Nussenzweig and his team focus on B lymphocytes and antibodies to HIV-1 in their work on adaptive immunity, while their studies of innate immunity focus on dendritic cells. Dr. Michel C. Nussenzweig. Michel C. Nussenzweig (born February 10, 1955) is a professor and head of the Laboratory of Molecular Immunology at The Rockefeller University and a Howard Hughes Medical Institute investigator. [8][9], "Contribution of dendritic cells to stimulation of the murine syngeneic mixed leukocyte reaction", "A monoclonal antibody specific for mouse dendritic cells", "Heads of Laboratory: Michel C. Nussenzweig", "Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice", "HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption", "Enhanced clearance of HIV-1–infected cells by broadly neutralizing antibodies against HIV-1 in vivo", "HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1", "AAI-Thermo Fisher Meritorious Career Award", "Twelve Howard Hughes Medical Institute Scientists Elected to American Academy of Arts and Sciences", "Institute of Medicine Elects 65 New Members, Five Foreign Associates", "Michel C. Nussenzweig elected to National Academy of Sciences", "Prêmio Diáspora Brasil divulga vencedores", "Toma de Posesión de Académico de Honor del Excmo. [1] He also produced the first dendritic cell-specific monoclonal antibody and cloned the first dendritic cell receptor. Institution. He earned a Ph.D. from The Rockefeller University in 1981 in cellular immunology, working in Zanvil A. Cohn’s laboratory with Ralph M. Steinman on groundbreaking studies of mouse dendritic cells. As a Ph.D. student, Nussenzweig was the first to show that dendritic cells present foreign antigens to initiate T cell immunity. Nussenzweig’s laboratory studies the molecular aspects of the immune system’s innate and adaptive responses using a combination of biochemistry, molecular biology, and genetics. In 2013, he was named the first Zanvil A. Cohn and Ralph M. Steinman Professor. Dr. Michel C. Nussenzweig is a Allergist-Immunologist in New York, NY. … from New York University School of Medicine in 1982 and completed his internship and residency in internal medicine, and a clinical fellowship in infectious diseases at Massachusetts General Hospital in 1985. Dr. Michel C Nussenzweig, MD is a Doctor primarily located in New York, NY. He received a B.S. HHMI shares the latest on our research, education, and organizational news. CURRICULUM VITAE . HHMI believes every student and citizen can experience science in a meaningful way. Michel Nussenzweig, MD . For work on adaptive immunity, he focuses on B lymphocytes and antibodies to HIV-1, while his studies of innate immunity focus on dendritic cells. Find Dr. Nussenzweig's phone number, address and more. In clinical trials, a broadly neutralizing antibody isolated from an HIV-infected patient was shown to be safe and effective and to interfere with chronic infection in a way that traditional antiretroviral therapy does not. Dr. Nussenzweig was born in Sao Paulo Brazil on February 10. th. [2], Nussenzweig received an M.D. degree from New York University College of Arts and Sciences in 1975. HHMI is a science philanthropy whose mission is to advance basic biomedical research and science education for the benefit of humanity. Make an Appointment + Locations, Office Hours & Directions. From 1986 to 1989, he was a postdoctoral fellow in genetics in the Harvard Medical School laboratory of Philip Leder. Through their work they aim to achieve a detailed understanding of the molecular basis of antibody production and the pathway of human dendritic cell development and differentiation. He has 29 years of experience. Dr. Nussenzweig is … Michel C. Nussenzweig, MD, PhD. HHMI supports people, rather than projects, because it’s individual scientists who break barriers to advance knowledge. Scientific Discipline. Dr. Nussenzweig completed a residency at Massachusetts General Hospital. He is a member of both the US National Academy of Medicine and the US National Academy of Sciences. Read patient ratings of Michel Nussenzweig, practicing Allergy & Immunology doctor in New York, NY Er studierte an der New York University mit dem Bachelor-Abschluss 1976. The team’s findings may help improve the effectiveness of vaccines for pathogens and therapies to prevent or control auto-immunity. Adaptive and Innate Immune Responses in Humans. [6][7] His research has led to the development of innovative vaccines against infectious diseases and new treatments for autoimmunity. 1230 York Avenue, The Rockefeller University, … Investigator / 1990—Present Dr. Nussenzweig is the Zanvil A. Cohn and Ralph M. Steinman Professor and a senior physician at The Rockefeller University. [5] The laboratory has isolated and cloned human antibodies to HIV-1 and explored their roles in prevention and therapy. Michel Nussenzweig is interested in the molecular aspects of the immune system’s innate and adaptive responses. Michel C. Nussenzweig (born February 10, 1955) is a professor and head of the Laboratory of Molecular Immunology at The Rockefeller University and a Howard Hughes Medical Institute investigator. Nussenzweig returned to The Rockefeller University as an assistant professor in 1990 and he became an associate professor in 1994, and a professor and senior physician in 1996. Dr. Michel Nussenzweig, MD is a internal medicine specialist in New York, NY. Er wurde 1981 an der Rockefeller University promoviert und erhielt 1982 seinen M.D. The Rockefeller University. His specialties include Clinical and Laboratory … HHMI empowers exceptional scientists and students to pursue fundamental questions in basic science. He is a member of both the US National Academy of Medicine and the US National Academy of Sciences Sr. D. Michel C. Nussenzweig", "The 2016 Rabbi Shai Shacknai Memorial Lecture in Immunology and Cancer Research", "With their outstanding research, laureates lay the foundation for understanding the way in which different immunological mechanisms function", "AAI-BioLegend Herzenberg Award Past Recipients", "JEM Editorial Board Co-Chair wins 2017 Sanofi-Institut Pasteur Award", https://en.wikipedia.org/w/index.php?title=Michel_C._Nussenzweig&oldid=927370658, Members of the National Academy of Medicine, Members of the United States National Academy of Sciences, Members of the Brazilian Academy of Sciences, Wikipedia articles with ORCID identifiers, Wikipedia articles with WORLDCATID identifiers, Creative Commons Attribution-ShareAlike License, Lee C. Howley Sr. Prize for Arthritis Research, 2008, Nobel Prize Lecture on behalf of Ralph Steinman, 2011, Rabbi Shai Shacknai Memorial Prize in Immunology and Cancer Research, 2016, This page was last edited on 22 November 2019, at 02:05.